参考文献
1．吉昌华.特异单引物法标记高活性DNA探针.第四军医大学学报.1991：12：62～85
2.Sambrokk J, Fritch EF, ManiatisT.Molecular Cloning –a laboratory Manual. 2nd. ed , Cold Spring HarbourLabortory Press, 1989
3. Cox KH, Deleon DV, Angeres LM,et al. Detection of mRNAs in sea urchin embryosby in situ hybridization usingasymmetric RNA probes. Dev Biol, 1984；101：485～489
4. Herrin DL, Schmidt GW. Rapidreversible staining of northern blots prior to hybridization. Biotechniques.1989；6：196～201
5. Khandjian EW. Optimizedhybridization of DNA blotted and fixed to nitrocellulose and nylon memdranes.Bio/Technology. 1987；5：164～170.
6.White BA, Bancroft FC.Cytoplasmic dot hybridization.Simple analysis of relative mRNA levels inmutiple small cell or tissue samples . J. Biol Chem. 1982；257：8569
7. Williams DL, Newman TC,Shelness CS, et al. Measurement of apolipoprotein mRNA by DNA –excess solutionhybridization with single –stranded probes. Methods Enzymol. 1986；128 ：671
8. 侯云德,主编.病毒基因工程原理与方法.P159～166.人民卫生出版社,1985；第1版,北京
9. Schleif RF & Wensink PC.Practical methods in molecualr biology. Springer –Verlag. 1981
10.林万明,主编.医学分子微生物学进展.第一集(上,下册).中国科学技术出版社,1991,北京
11.Mallet F. Enzyme –linkedoligosorbent assay for detection of immumodeficiency virus type 1. J ClinMicrobiol. 1993；31 ：1444～1449
12. Hall GS. Probe technology forthe clinical microbiology laboratory. Arch Pathol Lab Med 1993；117：578～83
13.林万明,主编,核酸探针杂交实验技术.中国科技出版社,1991；北京
14. Hajra A. Detection of humanDNA mutations with nonradioactive, allelespecifc oligonucleotide probes.Pharmacogenetics, 1992；2：78～439
15.Ogilvie AD. In situhybridization . Ann Rheum Dis. 1990；49：434～439
16. Levenson C, Watson R, SheldonEL. Biotinylated psoralen derivative for labeling nucleic acid hybridizationprobes. Methods Enzymol, 1990；184：577～583
17. Tenover FC. DNA hybridizationtechniques and their application to the diagnosis of infectious disease. InfectDis Clin North Am 1993；7：171～181
18. Landry ML. Nucleic acidhybridization in virol diagnosis.Clin Biochem 1990；23 ：267～277
19. Jackson P, Dockey DA, LewisFA, et al. Application of lnm gold probes on paraffin wax sections for in situhybridization histochemistry. j Clin Pathol 1990；43：810～812
20. Guesdon JL. Immunoenzymatictechiques applied to the specific detection of nucleic acids. A review. JImmunol Methods. 1992；150～49
21. Bush CE, Nichele LJ, PetersonWR, et al. Solid –phase time – resolved fluorescence detection of humanimmunodeficency virus polymerase chain reaction amplified products. AnalBiochem 1992；202：146～151
22.Cano RJ, Torres MJ, Klem RE,et al. DNA hybridization assay using ATTO PHOS, a fluorescent substrate foralkaline phosphatase.Biotechniques. 1992；12 ：264～269
23. Kallioniemi A, Goldstein F,Smith AR, et al. Comparative genomic hybridization for molecular cytogeneticanalysis of soid tumors.Science. 1992；258 ：(5083)：818～821
24. Terouanne B, Chung J –L,Williams S, et al.Quantitative and qualitative annalysis of amplified DNAsequences by a competitive hybridization assay. Anal Biochem. 1992；205 ：193～199
25. Marechal D. A subtractivehybridization method to isolate tissues – pecific transcripts application tothe selection of new brain ╟ specific products. Anal Biochem 1993；208：330～333
26.Goelz SE, Hamilton SR,Vogelstein B. Purification of DNa from formaldehyde fixed and paraffin embeddedhuman tissue. Biochem Biophys Res Commun. 1985；130 ：118
27. Debeau L, Chandler LA, GralowJR, et al. Sorthern blot analysis of DNA extracted from formalin – fixedpathology specimens. Cancer Res. 1986；46 ：2964
28. Mies C, Houldsworth J,Chaganti RSK. Extraction of DNa from paraffin blocks for Southern blotanalysis. Am J Surg Pathol, 1991, 15 ：169
29. Sato Y, Mukai K, Matsuno Y,et al. The AMeX method：a multipurpose tissue – processingand paraffinembedding method. II.Extraction of spooled DNA and its applicationto southern blot hybridization to southern blot hybridization analysis. Am JPathol. 1990；136 ：267
30. Mu AM, Ben –Bzra J, WinbergC, et al. Analysis of antigen receptor gene rearrangements in ethanol and formaldehyde– fixed,paraffin embeded specimens, Lab Invest . 1990；63 ：107
31.Mies C. Molecular pathology ofparaffin – embedded tissue：currentclinical applications. Diagn Mol Pathol. 1992；1：206
32. Koshiba M, Ogawa K, Ogawa O,et al. The effect of formalin fixation on DNA and the extraction of high –molecular weight DNa from fixed and embedded tissues. Path REs Pract . 1993；189 ：66
33.Bramwell NH, Burn BF. theeffects of fixative type and fixation time on the quantity and quality ofextractive DNA for hybridization studies on lymphoid tissue. Exp Hematol. 1988；16 ：730
34. 张建中晏良遂白炎,等.基因重排分析在淋巴瘤诊断中的应用.中华医学杂志,1988；16 ：730
35. Davis TH, Yockey CE, Balk SP.Detection of clonal immunoglobulin gene rearrangements by polymerase chainreaction amplification and sinle – strand comformational polymorphism analysis.Am J Pathol, 1993,142 ：184
36. Wick MR. Oncogene analysis indiagnostic pathology ：a current perspective. Am J ClinPathol, 1992；97 ：S1
37. Furcht LT, McGlennen RC. Theemerging role of molecular diagnositics in surgical pathology, 1992；23：1197
38. Sukpanichnant S, Vnencak–Jones CL, McCurley TL.Detection of clonal immunoglobulin heavy chain generearrangements by polymease chain reaction in scrapings from archival H –Estained histologic section.Diagn Mol Pathol, 1993；2：168
39. 张建中.分子杂交技术在淋巴瘤诊断中的应用,国外医学肿瘤学分册,1988；15 ：97
40.桂开林张建中. 甲状腺肿瘤的rasp 21表达的免疫组化观察.中华医学杂志,1990, 70：140
41. Wang Boyun (王伯沄),Li Yunsong (李云松),et al.Genetic identification for routine diagnosis of HBV by Dot – blot hybridization.Chinese Med J, 1993；106 (7)：550～551
