参考文献

1.Aird F,etal.Corticotropin-releasing factor mRNA in rat thymus and spleen.Proc Natl AcadSci USA,1993;90:7104 2.Amano Y,et al.Inhibition byglucocorticoids of the formation of interliukinlα，interleukinlβ and interleukin-6:mediation by decreasedmRNa stability.Mol Pharmacol,1993;43:176 3.Araujo DM.et al.Trophic effectsof interleukin-4,7 and 8 on hippocampla cultures:potential involvement ofglia-derived factor.Brain Res,1993;600:49 4.Ban EM,et al.Identification ofsuppressin-producing cells in the rat pituitary.Endocrinology,1993;133:241 5.Berkenbosch F,etal.CRF-producing neurons in the rat activated by interleukin-1.Science,1987;238:524 6.Bernadini R,et al.Rathypothalamic CRH secretion in vitro is stimulated by IL-1 in aneicosanoid-dependent manner.Life Sci,1990;47:1601 7.Berczi I.Pituitary function andImmunity.CRC Press Inc.Boca Raton Florida.1986 8.Buzzetti R,et al.A criticalassessment of the interactions between the immune system and thehypothalamus-pituitary-adrenalaxis.j Endocrinol,1989;120:183 9.Celada A,et al.Repression ofmajor histocompatibility complex I-a expression by glucocorticoids:theglucocorticoid receptor inhibits the DNa binding of the X box DNA bindingprotein.J Exp Med ,1993;177:691 10.Chao CC,et al.Activatedmicroglia mediate nediate neuronal cell injury via a nitric oxide mechanism.JImmunol,1992;149:2736 11.Christ M,et al.Theinositol-1,4,5-trisphosphate system is involved in repid effects of aldosteronein human mononuclear leukocytes.J cLIN eNDOCRINOl mETAB,193;77:1452 12.Cirino G,etal.Anti-inflammatory action of an N-terminal peptide from humanlipocortin-1,Brit J Pharmacol,1990;104:573 13.DuBois CM,et al.Hematopoieticgrowth factors and hlucocorticoids synergize to mimic the effects of IL-1 ongranulocyte differentiation and IL-1 receptor induction on bone marrow cells invi.Exp Hematol,1993;21:303 14.Effros RB,et al.Influence ofage and caloric restriction on macrophage IL-6 and TNF production.Lymphok CytokRes,1991;10:347 15.Flecher-Chiappini SE,etal.Glucocorticoid-prolactin interactions in Nb[XB]2[/XB]lymphomacells:antiproliferative versus anticytolytic effects.Proc Soc Exp BiolMed,1993;202:345 16.Freidin M and KesslerJA.Cytokine regulation of substance Pexpression in sympathetic neurons. ProcNatl Acad Sci UCA,1991;88:3200 17.Garcia I,et al.β-Endorphininhibits IL-2 release and expression of IL-2receptors in Con A-stimulatedsplenic lymphocytes.Lymphok Cytok Res,1992;11:339 18.Guilian D and LachmanL.Interleukin 1 stimulation of astroglial proliferation after graininjury.Science,1984;228:497 19.Haines KA,etal.Chemoattraction of neurtrophils by substance P and transforming growthfactor β1 is inadequately explained by current models of lipid remodelling.JImmunol,1993;151:1491 20.Hart RP,et al.Substance P geneexpression is regulated by interleukin-1 in cultured sympathetic ganglia.JNeurosci Res ,1991;29:282 21.Heagy W,et al.Opioid receptoragonists and Ca[SB]2+[/SB]modulation by interleukin-1 in cultured sympatheticganglia.J Neurosci Res,1991;29:282 22.Hiramoto R,etal.Identification of specific pathways of communication between the CNS and NKcell system.Life Sci,1993;53:527 23.Jonakati GM.Neural immuneinterations in sympathetic ganglia.TINS,1993;16:419 24.Katsuura G,et al.Interleukin-1beta increases prostaglanken E[XB]2[/XB] in rat astrocyte cultrues:modulatoryeffect of neuropeptides.Endocrinology,1989;124:3125 25.Kim KS,et al.Modulation ofbloodbrain barrier permeability by tumor necrosis facto and antibody to tumornecrosis factor in the rat.Lymphok Cytok rES,1992;11:293 26.kIMAALL ES,et al. SubstanceP,neurokinin A,and neurokinin Binduce generation of IL-1 like activity inP388D1 cells.j Immunol,1988;141:356427. 27.Koike K,et al.Tumor necrosisfactor-alpha increases release of arachidonate and prolactin from rat anteriorpituitary cells.Endocrinology,1991;128:2791 28.Kraiem A,et al.Effects ofgamma-interferon on Dr antigen expression,growth,3.5.3'-triidothyroninesecretion ,iodide uptake and cyclic adenosine monophosphate accumulation incultured human thyroid cells.j Clin Endocrin Metab,1990;71:817 29.Kroemer G,et al.Physiology andpathology of an immunoendocrine feedback loop.Immunol Today,1988;9:163 30.Lee SC,etal.Macrophage-colony-stimulating factor in human fetal astrocytes andmicroglia.Differential regulation by cytokines and lipopolysaccharide,andmodulation of class II MHC on microglia.j Immunol,1993;150:594 31.Louis J-C,et al. CNTFprotection of oligodendrocytes against natural and tumor necrosisfactor-induced death.Science,1993;259:689 32.Low KG,et al.Differentialregulation of proenkephalin expression in astrocytes bycytokines.Endocrinology,1992;131:1908 33.Lyson K,et al.Involvement ofarachidonic acid cascade in IL-6 stimulated CRF release invitro.Neuroendocrinol,1992;55:708 34.McGeer PL,et al.Reactivemicroglia are positive for HLA-Dr in the substantia nigra of Parkinson's andAlzheimer's disease brains.Neurology,1988;38:1285 35.Milenkovic L,et al.Cachectinalters anterior pituitary hormone release by a direct action in vitro.Proc Natl　Acad　Sci USA,1989;86:2418 36.Millington G and BuckinghamJC,Thymic peptides and neuroendocrine immunecommunication.JEndocrinol.1992;133:163 37.Muller H,et al.Interfaeronalpha 2-induced stimulation of ACTH and cortisol secretion inman.Neuroendocrinol,1991;54:499 38.Naiboh Y,et al.Interleukin-6stimulates the secretion of corticotropin in conscious freely movingrats.BBRC,1988;155:1459 39.Nistico G.Communications amongceutral nervous system,neuroendocrine and immune systems:interleukin 2.ProgrNeurodiol,1993;10:463 40.Nohava K,et al.Neurons andneuroblastoma as source of macrophage colony stimulating factor.Eur J Immunol. 41.Patterson PH and NawaH.Neuronal differentiation factors/cytokines and synaptic piasticity.Neuron10(suppl)1993;10(suppl):123 42.Perry VH,et al.Macrophages andinflammation in the central nervous system.TINS,1993;16:268 43.Rabin BS,et al.Bidirectionalinteraction between the central nervous system and the immune system.CriticalRev Immunol,1989;9:279. 44.Rogister B,et al.Transforminggrowth factor beta as a neuroglial signal during peripheral nervous systemresponse to injury.J.Neurosci Res,1993;34:32 45.Selmaj KW,et al.Proliferationof astrocytes in vitro in response to cytokines.A primary role for tumornecrosis factor.J Immunol,1990;144:129 46.Shieh　JH,et al.Cytokines and dexamethasone modulation ofIL-1receptors on human neutrophils in vitro.J Immunol.1993;150:3515 47.Spangelo BL,et al.Induction ofinterlukin-6 release by interleukin-1 in rat anterior pituitary cells invitro:Evidence for an eicosanoid dependent mehanism.Endocrinology,1991;129:2886 48.Spinedi E,et al.Cytokinestimulates the CRH but not the vasopressin neuronal system:evidence for amedian eminence site of interleukin-6action.Neuroendocrinol.1992;56:46 49.Tsagarakis S,etal.Interleukin-1 directly stimulates the release of corticotropin releasingfactor from rat hypothalamus,Neuroendocrinol,1989;49:98 50.Tsitsiloni OE,et al.Expressionof α-thymosins in human tissues in normal and abnormal growth.Proc Natl AcadSci USA.1993;90:9504 51.Vankelecom H,et al.Evidencethat folliculostillate cells mediate the inhibitory effect of interferon-γ onhormone secretion in rat anterior pituitary cell cultures.Endocrinology,1992;130:3537 52.Yamashita H,et al.Effects ofintekleukin 1β on membrane potentials of hypothalamic meurons in rats invitro.Amm NY Acad Sci,1993;689:689 53.徐仁宝.躯体性和心理性应激.复量神经生物学讲座.1991；7：85